Nature’s precision to control food pathogens

In nature, predator–prey relationships keep ecosystems in balance. In the same way, bacteria are also balanced by a natural predator. Bacteriophages (phages) fulfil this role, ensuring bacterial populations stay dynamic rather than uncontrolled. Phageguard enhances the precise targeting ability of phages for industrial control of food pathogens, offering antimicrobial phage solutions that are non-hazardous, non-corrosive, and which preserve the sensory attributes of treated foods. USA: Phageguard products hold FDA GRAS status for clean-label processing.

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Welcome to the power of phages

Wherever bacteria are found, even more phages are present, each with its own vital role in regulating a specific type of bacterium. This includes phages that specifically target Salmonella, Listeria, or E. coli (STEC). When these phages are applied to food, they inactivate only the food pathogen of concern, preserving all attributes directly related to product quality.

For example, if we apply a Salmonella targeting phage to chicken meat, it will inactivate the Salmonella bacterium as soon as it makes contact. When that same phage encounters beneficial bacteria or the food’s own cells, nothing happens. As a result, phages preserve the taste, texture, color, and odor (sensory attributes) of the treated chicken meat. The outcome: a safer, natural food product that offers its maximum nutrition and taste.

Bacteriophage's lytic cycle for inactivating food pathogens

The process of bacterial inactivation by bacteriophages is called the lytic cycle. This is a process in which a bacteriophage attaches to its host bacterium, infects, and replicates. Although the lytic cycle contains multiple steps as presented below, industrial implementations supported by lab studies present rapid reductions of our phage solutions (as a result of the lytic cycle) within several minutes post-application.

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Recognition

The phage floats freely driven by random Brownian motion until it encounters the harmful bacteria.
02

Attachment

The phage interacts with the harmful bacterium.
03

Interaction

The phage interacts with the harmful bacterium.
04

Replication

The phage uses the harmful bacterium to create new phages.
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Lysis

The bacterium is neutralized and dissipates, releasing new phages.

What makes our technology different?

Phage technology ensures that only the harmful bacteria are eliminated—leaving everything else, from beneficial microbes to product quality, untouched.


What makes our technology different?

01

Scientifically validated by renowned universities and research institutions (ETH, WUR, University of Nevada, Reno among 40+ others)

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Recognized by leading governmental agencies across the world (FSIS, FDA, EFSA, Health Canada, FSANZ among others)

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Compatible with existing process workflows: from in-line sprays to dip tanks

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Pre-selected phages for maximum efficacy against the most common and persistent strains in the food industry, without the need for phage cocktails

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We are proud partners – teaming up with industry experts

Discover the power of our phage technology

Our phage solutions are trusted by food processors across industries, food safety departments, and regulatory authorities worldwide. Resulting in our solutions being validated in over 60+ peer-reviewed publications.
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Whats new

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News
December 10th, 2023 3 min A worldwide distributor network to improve food safety management systems
News
September 20th, 2023 5 min Advancing phage technology: Our response to the FAO & WHO report on produce safety
Phage fact Phages can be found in all environments such as soil and water
Phage fact Phages have been used as a natural alternative to antibiotics for treating humans
Phage fact Phages are 10 to 100 times smaller than bacteria
Phage fact A small bottle of Phageguard contains 20 trillion phages